- Original Article
- Prognostic factors in children with extracranial germ cell tumors treated with cisplatin-based chemotherapy
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Jinsup Kim, Na Hee Lee, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo, Jeong-Meen Seo, Suk-Koo Lee
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Clin Exp Pediatr. 2015;58(10):386-391. Published online October 21, 2015
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Purpose To evaluate the outcomes and prognostic factors in children with extracranial germ cell tumors (GCTs) treated at a single institution. MethodsSixty-six children diagnosed with extracranial GCTs between 1996 and 2012 were included in the study. Primary treatment was surgical excision, followed by six cycles of cisplatin-based chemotherapy. The survival rates were compared according to the International Germ Cell Cancer Cooperative Group... |
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- Case Report
- A fatal case of acute pulmonary embolism caused by right ventricular masses of acute lymphoblastic lymphoma-leukemia in a 13 year old girl
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Yu Mi Ko, Soo Hyun Lee, June Huh, Hong Hoe Koo, Ji Hyuk Yang
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Clin Exp Pediatr. 2012;55(7):249-253. Published online July 17, 2012
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We report a case of a 13-year-old girl with acute lymphoblastic lymphoma-leukemia, who presented with a cardiac metastasis in the right ventricle, resulting in a pulmonary embolism. At the time of her leukemia diagnosis, a cardiac mass was incidentally found. The differential diagnosis for this unusual cardiac mass included cardiac tumor, metastasis, vegetation, and thrombus. Empirical treatment was initiated, including... |
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- Original Article
- Hematopoietic stem cell transplantation in children with acute leukemia: similar outcomes in recipients of umbilical cord blood versus marrow or peripheral blood stem cells from related or unrelated donors
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Eun Sang Yi, Soo Hyun Lee, Meong Hi Son, Ju Youn Kim, Eun Joo Cho, Su Jin Lim, Hee Won Cheuh, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo
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Clin Exp Pediatr. 2012;55(3):93-99. Published online March 16, 2012
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Purpose This study compared outcomes in children with acute leukemia who underwent transplantations with umbilical cord blood (UCB), bone marrow, or peripheral blood stem cells from a human leukocyte antigen (HLA)-matched related donor (MRD) or an unrelated donor (URD). MethodsThis retrospective study included consecutive acute leukemia patients who underwent their first allogeneic hematopoietic stem cell transplantation (HSCT) at Samsung Medical Center between... |
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- The metabolic syndrome and body composition in childhood cancer survivors
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Young Bae Sohn, Su Jin Kim, Sung Won Park, Se-Hwa Kim, Sung-Yoon Cho, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Jae Hoon Chung, Hong Hoe Koo, Dong-Kyu Jin
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Clin Exp Pediatr. 2011;54(6):253-259. Published online June 30, 2011
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Purpose Long-term survivors of childhood cancer appear to have an increased risk for the metabolic syndrome, subsequent type 2 diabetes and cardiovascular disease in adulthood compared to healthy children. The purpose of this study was to investigate the frequency of the metabolic syndrome and associated factors in childhood cancer survivors at a single center in Korea. MethodsWe performed a retrospective review of... |
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- Responses and adverse effects of carboplatin-based chemotherapy for pediatric intracranial germ cell tumors
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Suntae Ji, Hee Won Chueh, Ju Youn Kim, Su Jin Lim, Eun Joo Cho, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo
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Clin Exp Pediatr. 2011;54(3):128-132. Published online March 31, 2011
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Purpose Cisplatin-based chemotherapy has been commonly used for the treatment of intracranial germ cell tumors (IC-GCTs). However, this treatment exhibits some adverse effects such as renal problems and hearing difficulty. Carboplatin-based chemotherapy was administered to pediatric patients with IC-GCTs from August 2004 at the Samsung Medical Center. In this study, we assessed the responses and adverse effects of carboplatin-based chemotherapy in... |
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- Erratum
- A new strategy for transcatheter closure of patent ductus arteriosus with recent-generation devices
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Sang Yee Kim, Soo Hyun Lee, Nam Kyun Kim, Jae Young Choi, Jun Hee Sul
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Accepted January 1, 1970
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Purpose : The aim of this study was to assess the efficacy and safety of recent-generation patent ductus arteriosus (PDA) closure devices applied by a new selection strategy according to the characteristics of each PDA.
Methods : From February 2003 to January 2006, 138 patients underwent transcatheter closure of PDA (study group). According to the size and morphology of each... |
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- Allogeneic Hematopoietic Stem Cell Transplantation in Juvenile Myelomonocytic Leukemia
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Keon Hee Yoo, Dong Kil You, Soo Hyun Lee, Ki Woong Sung, Eun Joo Cho, Hong Hoe Koo
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Clin Exp Pediatr. 2005;48(2):178-185. Published online February 15, 2005
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Purpose : The purpose of this study was to evaluate the outcome of children with juvenile myelomonocytic leukemia(JMML) treated with allogeneic hematopoietic stem cell transplantation(allo- HSCT).
Methods : Eleven JMML patients aged 8-39 months underwent allo-HSCT. The sources of grafts were unrelated donors(n=7), HLA-matched siblings(n=3) and an HLA 1-antigen mismatched familial donor. All patients had received chemotherapy ?13-cis-retinoic acid(CRA) before... |
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- Responses and Toxicities of Risk-adapted Chemotherapy in Pediatric Intracranial Germ Cell Tumors
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Dong Kil You, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Do Hoon Lim, Hyung Jin Shin, Hong Hoe Koo
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Clin Exp Pediatr. 2005;48(2):186-190. Published online February 15, 2005
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Purpose : The purpose of this study was to evaluate the responses and toxicities of risk-adapted chemotherapy in pediatric intracranial germ cell tumors(IC-GCT).
Methods : Fourteen patients who were diagnosed as IC-GCT from October 2002 to December 2003 received chemotherapy as an initial treatment modality. The low risk(LR) group was defined as follows : Pure germinoma and normal AFP level.... |
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